2nd Unseminar: Funding Bioinformatics

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What? Meet fellow bioinformaticians in Heidelberg, and discuss Funding Bioinformatics

When? Tuesday June 26th, 2012, 19.00 - 21.00

Where? Grabengasse 3-5, Building 2170, Groundfloor, Hörsaal 09.

How? The 2nd HUB will feature talks and discussions, but you get to shape the programme.

Who is organising it? A team of people working at several different life-science organisations within Heidelberg are organising HUB, with your help.

Who is coming? Check out the list of registered participants

Results of survey from 1st unseminar

Checklist of tasks before the meeting

Programme

19:00 Arrival & Introduction
19:05 Intro to bioinformatics at an HD institution: HITS, introduced by Jon Fuller
19:15 Financing entrepreneurial efforts in life sciences, Martin Holi, with extended Q&A.
19:45 Elevator pitch - present your projects to your neighbour.
20:05 Flash talk: a mathematical model of hindgut curvature, Joe Barry
20:15 Discussion session: successfully obtaining funding.
20:50 Wrap up session: Dates for next HUB, choosing flash talks
21:00 To the pub i.e. Essighaus, Plöck 97

Your contributions to shaping the programme

Propose a Discussion Topic

Always wondered how others deal with a challenge you frequently face? Have a proven approach to a problem, or know someone who does? This is the place to put forward what keeps you up at night, and what gets you out of bed in the mornings.
Suggest a topic and a good person to moderate the discussion (this can be you, of course), or add your thoughts on the current suggestions:

Crowd Funding?: a new source of funding for bioinformatics projects?

Proposed structure:

  • Introduction to crowd funding in general, and one possible bioinformatics project (Grischa) (max 10 minutes)
    • What is crowd funding?
    • What features of proposals help them get funded?
    • What kind of sums have been involved?
    • An idea for a possible crowd-funded project
  • Small group discussions - brainstorming to identify possible projects, identifying key strengths/weaknesses of proposals (max 10 minutes)
  • Whole group survey/description of possible projects coming from brainstorming (15 minutes)
  • Conclusion - what could we try and do with these ideas? (5 minutes)

Funding entreprenuerial efforts

  • Moderated by: Martin Holi
  • Proposed by: Matthew and Martin Holi

Martin's 10min talk beforehand will cover grants for commercialisation:

  • what are they good for?
  • how do they work?
  • what are their differences?
  • potential applicants?

The aim of our proposed discussion topic is to get people thinking about issues in applying for 'non-traditional' money. Martin will briefly present a case study of a start-up project that has applied for grants, then we will split in to small groups to discuss this for ca. 10 minutes, around four main area:

  1. Team
  2. Intellectual Property
  3. Innovation
  4. Market & competition

with each group rating the case-study in one or more of those areas, thinking of potential issues and how they would address them.

Each group will then present/discuss their results with everyone, with the opportunity to compare to what Martin did in the case study.

Successfully obtaining funding

Proposed structure:

    • Short presentation and questions: Applying for Public Funding (Reinhard Schneider, University of Luxembourg) (15 min)
    • Survey/exploration of funding experience at the meeting (via show of hands) (5 min)
    • Small group discussions, grouping based on experience of different kinds of funding from the room (e.g. travel grants, large EU grants, postdoc/predoc fellowships, ERC, but also private funding, venture capitalists, if lots of people want to discuss this:
      • together try to write (5? 10?) features of excellent/successful grants, and of unsuccessful grants
      • write these on sheets of paper, given in to organisers at the end, will be put on wiki after the event (10 min)
    • Short whole-group discussion: Any tips/ideas for successful applications that surprised you, that you found particularly good (5-10 min)

Short length proposals

Topics for discussion (implementation, content, context and extent can vary on demand and interest):

  • Scientific writing and presentation skills (could be a tutorial or be an exchange of ideas and experiences)
  • Where do GOOD ideas come from?
  • Industry or academia? Pros and cons - And how to reach my goals? How can I know what to aim for in my career?
  • What makes a project successful and ... sexy (hmm ... i.e., deserving funding)? Am I realistic about it? How do I design one? When should I stop running a task/project?
  • I need to interview (or be interviewed by) someone! Now what?
  • Is there a thing such as time-management? I am overloaded constantly.
  • Are there minimum bioinformatic skills? What is the network of the fields that bioinformatics study?
  • Bioinformatics challenges: which are they? (e.g., visualization, sequencing, large data sets, networks, need for a common data sharing and exchange platform/language, or more?)
  • Bioinformatics beyond biology - are there new trends? (e.g., medicine, chemistry)

Propose a Flash Talk

Please take a look at the Guidelines.

Adding details to interaction networks

  • Matthew Betts
  • CellNetworks / University of Heidelberg
  • Many experimental methods for detecting protein-protein interactions tell us what interacts with what but not how. Protein 3D structure can provide these details in many cases. I'll explain how we use protein structure to explain interactions and to predict new ones, and how we use it to investigate the impact of mutations and post-translational modifications.

Fitting high throughput data to a Boolean network model

  • Guy Karlebach
  • DKFZ - Heidelberg
  • Fitting between a high throughout dataset and a Boolean network model is an interesting problem with practical implications. In this flash talk I define the problem, analyze its complexity and present an algorithm for it.
  • The talk is based on the following paper

A mathematical model of hindgut curvature

  • Joseph Barry
  • EMBL-Heidelberg
  • A novel mechanism for the maintenance of hindgut curvature in the developing Drosophila embryo is explained in the context of intercellular adhesion and the differential interfacial tension hypothesis.

PhenoTimer: connecting time-resolved phenotypes

  • Maria Secrier
  • EMBL-Heidelberg
  • Connecting genetic and phenotypic information in the context of temporal variation is an ongoing challenge in systems biology. I will introduce PhenoTimer, a visualization tool for mapping time-resolved phenotypic links in a genetic context. Its capabilities in discovering dynamic regulatory patterns within the cell cycle and potential in identifying links between diseases will be illustrated.